Institute of Molecular Genetics of the Czech Academy of Sciences
| Grant name | Provider | Duration | Investigator | Web |
|---|---|---|---|---|
| Germline, weakly activating JAK2 variants predisposing to myeloid malignancies: cooperation with driver leukemogenic oncogene | Ministry of Health | 2021-2024 | L. Láníková | |
| National Cancer Institute | Ministry of Education, Youth and Sports | 2022-2025 | V. Kořínek | Go to website |
| Role of DNA damage response in suppressing malignant progression in preleukemia conditions of some myeloproliferative and myelodysplastic neoplasms | Czech Science Foundation | 2024-2026 | L. Láníková |
| Grant name | Provider | Duration | Investigator | Web |
|---|---|---|---|---|
| High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer. | Ministry of Education, Youth and Sports | 2006-2011 | V. Kořínek | Go to website |
| Tumor suppressors in the Wnt signaling pathway | Czech Science Foundation | 2007-2010 | V. Kořínek | Go to website |
| Bacteria in etiology, prevention ant therapy of experimentally induced intestinal inflammation and colon cancer | Czech Science Foundation | 2011-2014 | V. Kořínek | Go to website |
| Wnt signaling in self-renewal and tumorigenesis of the intestinal epithelia | Czech Science Foundation | 2011-2014 | V. Kořínek | Go to website |
| Molecular mechanisms of the tumor suppressor function of the HIC1 gene | Czech Science Foundation | 2012-2015 | V. Kořínek | Go to website |
| Founding the Centre of Transgenic Technologies | Ministry of Education, Youth and Sports | 2012-2015 | R. Sedláček, V. Kořínek, Z. Kozmík | Go to website |
| Development of new chemical compounds with anti-tumor activities or use in regenerative medicine | Ministry of Industry and Trade | 2012-2015 | P. Bartůněk, V. Kořínek | Go to website |
| Molecular mechanisms underlying cell-fate decisions in the intestine | Czech Science Foundation | 2014-2016 | V. Kořínek | Go to website |
| Biomodels for Health – Center for Model Organisms | Ministry of Education, Youth and Sports | 2015-2019 | P. Bartůněk, J. Hejnar, O. Horvath, V. Kořínek, Z. Kozmik, D. Staněk, P. Svoboda | Go to website |
| Molecular pathophysiology of erythroid disorders | Ministry of Education, Youth and Sports | 2015-2017 | L. Láníková | Go to website |
| Molecular bases of clonal heterogeneity and progression of polycythemia vera | Czech Science Foundation | 2015-2017 | L. Láníková | Go to website |
| The Wnt signaling network – novel components and regulatory mechanisms | Czech Science Foundation | 2015-2017 | V. Kořínek | Go to website |
| Diet and microbiota as modulators of gut inflammation and colon cancer | Czech Science Foundation | 2016-2018 | V. Kořínek | Go to website |
| Genetické predispozice k myeloproliferativním onemocnění v JAK/STAT dráze | Ministry of Education, Youth and Sports | 2017-2021 | L. Láníková | Go to website |
| Initiation and progression of myeloproliferative disorders - the role of pathological JAK2 activation in the specific context of EPOR | Czech Science Foundation | 2017-2019 | L. Láníková | Go to website |
| Principal signaling pathways regulating NG2 glia proliferation and defferentiation following brain injuries | Czech Science Foundation | 2017-2019 | V. Kořínek | Go to website |
| The canonical Wnt pathway components involved in non-canonical signaling mechanisms | Czech Science Foundation | 2018-2020 | V. Kořínek | Go to website |
| Wnt ligands and Wnt-secreting cells for intestinal homeostasis, regeneration and colon cancer: a complex world beyond the cancer-activating mutation | Czech Science Foundation | 2018-2020 | T. Valenta | Go to website |
| Cellular and molecular-genetic characterization of selected hereditary defects of erythropoiesis | Ministry of Health | 2019-2022 | L. Láníková | Go to website |
| Role of LGR5-positive stem cells in odontogenesis | Czech Science Foundation | 2019-2021 | V. Kořínek | Go to website |
| Mechanisms of initiation of early gut tumour stages and regeneration of gut epithelium | Czech Academy of Sciences | 2020-2022 | M. Šťastná | |
| Characterization of early stages of intestinal tumorigenesis induced by non-physiological activation of Wnt signaling | Czech Science Foundation | 2020-2022 | V. Kořínek | Go to website |
| Transformations of the gastrointestinal stem cell niche during the development and regeneration | Czech Science Foundation | 2021-2023 | T. Valenta | Go to website |
| Involvement of Wnt/β-catenin signaling in neurogenesis and gliogenesis following brain ischemic injury - analysis at the single cell level | Czech Science Foundation | 2021-2023 | V. Kořínek | Go to website |
