References from our Partners

Licensing agreement with Seattle Genetics (provision of cDNA encoding a specific monoclonal antibody)

Application:
Construction of a potential therapeutic product.

Partner organisation:

Experimental development of a multimodal holographic microscope – a revolutionary prototype microscope based on incoherent holography

Partner organisation:

Plasmid for the expression of rec. Strep-TRItag-TRAIL for selective precipitation of TRAIL-TRAIL-R complexes

Monoclonal antibodies against the cytoskeletal protein NFH. Preparation and characterization of monoclonal antibodies recognizing the human Abraxas‑1 protein. Plasmids expressing recombinant hAPP‑IgG and hAPLP2‑IgG proteins. Preparation and characterization of human LGR5 protein and polyclonal antibodies recognizing human LGR5 protein.

Result obtained in the project:
Centre for Molecular and Cellular Immunology

Application:
at the contractor Exbio Praha a.s.

Partner organisations:

15 hybridoma lines prepared within the project

Result obtained in the project:
Structure and disorders of the nucleoskeleton of the cell nucleus – identification and diagnosis

Provider:
TA CR

Partner organisation:

Construction of nanofibrous carriers incorporating cyclosporin A and carrying stem cells for therapeutic applications

Result obtained in the project:
Biocompatible nanofibrous constructs creating novel dosage forms for the application of biologically and pharmacologically active agents

Partner organisations:

A new method for the determination of low concentrations of proteins in complex biological fluids by nano-iPCR

Result obtained in the project:
Nano-PCR, an ultrasensitive test for the detection of specific proteins in body fluids

Partner organisations:

Monoclonal antibodies 2E3.H3.F2, 4C6.D12.D2, 5G3.E1.G9, 5G3.E5.A8 and 6B4.E9.B4 attached to gold nanotubes

Result obtained in the project:
New nanoparticles for ultrastructural diagnostics

Partner organisation:

Aptamer inhibiting the enzymatic activity of Taq DNA polymerase

Application:
Prototyp soupravy pro Hot start PCR s aptamerem inhibujícím enzymatickou aktivitu Taq DNA polymerázy.

Result obtained in the project:
New Generation of DNA Aptamers

Provider:
TA CR

Partner organisation:

Use of nanofibrous carriers for stem cell transfer for therapeutic purposes

Result obtained in the project:
Biocompatible nanofibrous constructs creating novel dosage forms for the application of biologically and pharmacologically active agents

Partner organisations:

Preparation of monoclonal antibodies against CLIC5a, LARGE and OPAL1 proteins

Result obtained in the project:
Centre for Molecular and Cellular Immunology

Application:
at the contractor Exbio Praha a.s.

Partner organisations:

Conjugated nanoparticles with antibodies of hybridoma lines 2E3-41, 3B6-3, 4C6-37, 5G3-51, 6B4-56, 6B4-57, 6D6-16 and 6D6-34, prepared within the project “New nanoparticles for ultrastructural diagnostics”

Partner organisation:

New universal qPCR mixes. Results obtained in the Nano-PCR project, an ultrasensitive assay for the detection of specific proteins in body fluids

Partner organisations:

Certified methodology (procedure) – Qualitative detection of viral vaccine antigens

Result obtained in the project:
New nanoparticles for ultrastructural diagnostics

Partner organisation:

Monoclonal antibodies 2E3.H3.F2, 3B6.0.C7, 4C6.D12.D2, 5G3.E5.A8, 6B4.E9.B4, 6B4.E9.B6, 6B4.E9.B12 and 6D6.F10.D12 attached to cubic palladium nanoparticles

Result obtained in the project:
New nanoparticles for ultrastructural diagnostics

Partner organisation: