Core Facilities Services

We provide services to our employees and to organizations outside IMG as part of research services, research-service groups and research infrastructures.

To find the contact details for the relevant services, click on the service link.

What do you need help with?

Generation of custom mouse models

Development and breeding of mutant lines (including SPF strains), genotyping, cryopreservation of sperm and embryos and follow-up services.

Phenotyping of mouse and rat models

Characterization of cardiovascular and pulmonary function, metabolic, biochemical and neurobehavioral analysis, functional testing of vision and hearing.

In-vivo imaging of mouse and rat models

Fluorescence and bioluminescence imaging of developmental and pathological changes, 3D visualization of adult individuals and embryos.

Generation of other biological models

Development of unique mutant lines of zebrafish, chickens, clawed frogs, nematodes, lampreys, amphioxi and annelids.

Preclinical testing in animal models

Toxicological and pharmacological studies in rodents and non-rodents, development of diagnostic methods, synthesis, characterisation and certification of chemicals.

Development and production of monoclonal antibodies

Preparation of mouse monoclonal antibodies (including ELISA testing), cloning of hybridoma lines and storage in cryobank.

Development of screening and biochemical assays

Preparation and optimization of high-throughput screening methods, development of biochemical and cell-based assays according to the requirements of researchers.

Genomics and bioinformatics analysis

Processing and sequencing of DNA and mRNA samples, preparation of DNA libraries, analysis of the obtained data.

Proteomics analysis

Preparation of samples, peptide analysis by mass spectrometry, evaluation of acquired data.

Flow cytometry

Cell analysis on flow cytometers, analysis of collected data, user training.

Light microscopy and image analysis

Access to advanced light microscopes and image analysis software, services ranging from experimental design, image data acquisition to image processing and analysis.

Cryo-electron microscopy

Access to transmission electron microscopes and sample preparation technologies, user training and support, experimental design, data processing, custom method development and optimization.