To find the contact for the relevant facility, click on the link by the particular equipment.
Light microscopy – advanced light and fluorescence microscopes with, among others, quantitative phase imaging (QPI), laser scanning (LSCM), stimulated emission depletion (STED), localization microscopy (STORM) or fluorescence recovery after photo-bleaching (FRAP).
Electron microscopy – transmission electron microscopes (JOEL) and cryo devices, Leica microtomes for automated and manual sample preparation.
Nucleic acid processing and sequencing – equipment for DNA and RNA sample sequencing (Illumina NextSeq 500 and Oxford Nanopore Minion Mk1b sequencers), for genomic library preparation and transcriptome sequencing (10x Genomics Chromium Controller and Bio-Rad ddSEQ) and for detection of genes and mutations of interest (Illumina BeadStation 500 microarray platform and PerkinElmer EnVision Plate Reader).
Protein processing and sequencing – equipment for proteolysis, peptide separation (UHPLC Ultimate 3000 liquid chromatograph) and proteomic analysis (Orbitrap Exploris 480 spectrometer).
Cytometry – laser flow cytometry equipment (BD FACSymphony Flow Cytometer, Luminex Amnis ImageStream X Mk II), cell sorters (BD Influx Cell Sorter, BD Biosciences FACSAria IIu and Miltenyi Biotec autoMACS Pro Separator) and advanced image analysis software (FlowJo).
Identification and development of novel molecular probes and therapeutic compounds and biochemical profiling – systems for High-Throughput Screening, High-Content Screening and Compound Management (including quality control).
The Czech Centre for Phenogenomics also includes a unit for the preparation of new mutant lines.