The main aim of the two-week course is to inform the participants about the recent progress in the ﬁelds of molecular biology, genetics and biomedicine together with selected new biotechnology approaches.
Typical attendees are the ﬁrst and second year PhD students from biomedical programs, but other participants are also very welcome. The main aim of the two-week course is to inform the participants about the recent progress in the ﬁelds of molecular biology, genetics and biomedicine together with selected new biotechnology approaches. The course is accredited (MPGS0034) at the Charles University.
All lectures will be held in English by active scientists.
The course is composed of ~ 40 lectures organized into the following thematic blocks:
DNA/cell nucleus: nuclear microstructure-function and regulation, evolution of telomeres and telomerase activity, DNA repair, evolution of gene expression regulation.
RNA: molecular biology of RNA polymerases, alternative splicing regulation, RNA modiﬁcations, small RNAs.
Proteins: eukaryotic protein synthesis, 3D structure of proteins, X-ray crystallography, cryogenic electron microscopy (CryoEM), protein folding prediction, proteomics and proteomes, ubiquitin-mediated protein degradation, RNA-protein interaction.
Cell biology and signaling: microtubules and signal transduction, membrane microdomains, cellular iron-oxidative stress-DNA damage-ferroptosis, biological clock, eukaryotic ﬂagella and cilia, Wnt signaling.
Development: germline reprogramming, oocyte-to-embryo transition, insect genetic models for hormonal regulation of development, hematopoesis, Notch signaling.
Genetics and genomics: structure and evolution of the SARS-CoV-2 genome, CRISPRs, analysis of complex plant genomes, gene editing in antiviral research.
Biomedicine: current concepts in tumor imunology and immunotherapy, prion strains and diseases, genetics of unsolved rare diseases, genetics of intellectual disability and autism, molecular and genetic bases of bacterial virulence, DNA damage response and cellular checkpoints in cancer.
Workshops: English in academic writing. Career paths in science-research and alternatives. Decision points: postdoc selection and postdoc interview. Research ethics and misconduct. Discussion panel: Life with science.
At the end of the course participants receive the credit and the presentations will be available for download from a password-protected website.
For more information and online registration, please visit – https://pokroky.img.cas.cz/.
Deadline: October 22, 2021