Laboratory of Viral and Cellular Genetics

Current Grants

Grant name Provider Duration Investigator Web
Praemium Academiae Czech Academy of Sciences 2019-2024 J. Hejnar
Antiviral Action of Avian Tetherin/BST2 Czech Science Foundation 2020-2022 D. Elleder Go to website
Virology and antiviral therapy Czech Academy of Sciences 2021-2025 J. Hejnar, R. Sedláček Go to website
Mechanism of somatic hypermutation targeting in the B cell genome Czech Science Foundation 2022-2024 F. Šenigl
National Institute of Virology and bacteriology (NIVB) Ministry of Education, Youth and Sports 2022-2025 J. Hejnar

 

Past Grants

Grant name Provider Duration Investigator Web
Engineering of the porcine genome for xenotransplantation studies in primates: a step towards clinical application Sixth Framework Programme EU 2006-2012 J. Hejnar Go to website
The role of DNA methylation and histone modifications in the establishment and maintenance of HIV-1 latency Czech Science Foundation 2008-2010 J. Blažková Go to website
Fusogenic envelope glycoproteins of human endogenous retroviruses and their receptors Czech Science Foundation 2009-2011 J. Hejnar Go to website
Transcriptional silencing of retroviral vectors during their integration into the host genome Czech Science Foundation 2009-2011 F. Šenigl Go to website
Characterization of new avian sarcoma and leukosis virus (ASLV) receptor alleles as revealed by the analysis of semi-resistant cells Czech Science Foundation 2010-2012 J. Plachý Go to website
Avian Sarcoma and Leukosis Virus-based Vectors and Their Potential for Transgenesis in Chicken Czech Science Foundation 2011-2013 J. Hejnar Go to website
Development of CpG methylation of HIV-1 promoter and its stabilizing effect on the latent provirus reservoir: longitudinal study in patients Czech Science Foundation 2012-2014 K. Trejbalová Go to website
New type of vaccine against chicken viral diseases Ministry of Agriculture 2012-2016 J. Hejnar, D. Kučerová Go to website
Regulation of active endogenous retroviruses in the mammalian genome Ministry of Education, Youth and Sports 2012-2016 D. Elleder Go to website
Syncytins as markers of germ line tumors Ministry of Health 2013-2015 J. Hejnar Go to website
Expression of fusogenic human endogenous retroviruses in germ line tumors. Czech Science Foundation 2013-2015 J. Hejnar Go to website
Chicken polymorphisms in retroviral receptors and their potential for cross-species transmission Czech Science Foundation 2013-2015 J. Plachý Go to website
Sensing of HIV-1 by plasmacytoid dendritic cells: dichotomy of immunoreceptor signaling Czech Science Foundation 2014-2016 I. Hirsch Go to website
Epigenomics of retroviral integration Czech Science Foundation 2014-2016 J. Hejnar Go to website
Advancing reverse genetic technologies for the chicken Czech Academy of Sciences 2015-2016 J. Hejnar
Biomodels for Health – Center for Model Organisms Ministry of Education, Youth and Sports 2015-2019 P. Bartůněk, J. Hejnar, O. Horvath, V. Kořínek, Z. Kozmik, D. Staněk, P. Svoboda Go to website
Analysis of Rous sarcoma virus replication blocks in non-permissive cells and characterization of factors contributing to virus rescue Czech Science Foundation 2015-2017 J. Geryk Go to website
Gene targeting in chicken and the resistance to newly emerging retroviruses Czech Science Foundation 2015-2017 J. Hejnar Go to website
Mistargeting of somatic hypermutation and its role in B cell genome instability Czech Science Foundation 2015-2017 F. Šenigl Go to website
Evolution of endogenous retroviruses and ther role in cancer Czech Academy of Sciences 2015-2016 M. Matoušková
Functional characterization of Avian Sarcoma and Leukosis Virus receptors Czech Science Foundation 2017-2019 D. Elleder Go to website
Interactions of syncytins with specific cell receptors Czech Science Foundation 2017-2019 J. Hejnar Go to website
Polymorphisms in cellular receptors for avian leukosis virus Czech Academy of Sciences 2017-2018 J. Hejnar
The mechanism of assembly of nucleus - anchored actin filaments and their role in the cancer invasion and metastasis Czech Science Foundation 2018-2020 J. Plachý Go to website
Advancement of chicken transgenic technology and its biotechnological application Ministry of Agriculture 2018-2021 J. Hejnar Go to website
Transgenic models of transposon insertional mutagenesis in domestic chicken Czech Science Foundation 2019-2021 J. Hejnar Go to website

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