Head of the Genome Engineering and Model Generation Unit
The Czech Centre for Phenogenomics at the Institute of Molecular Genetics of the Czech Academy of Sciences, a member of the IMPC and INFRAFRONTIER consortia, offers an exciting opportunity for an experienced and motivated expert to lead the Genome Engineering & Model Generation Unit within the Transgenic and Archiving Module (TAM).
This is an exciting opportunity to oversee cutting-edge research and services in the development of genetically modified rodents, utilizing the latest genome editing technologies. The unit provides comprehensive services—from gene-targeting design to generation, cryopreservation, and breeding of rodent models for phenotyping and research.
Your responsibilities
- Leadership & Management: Lead and coordinate the entire model production process—from initial design to genotyping and colony management. Supervise the team of laboratory technicians, oversee services, experiments, and ensure smooth workflow within TAM.
- Hands-on Technical Work: Directly participate in generating genetically modified rodents (mouse, rat) using methods such as microinjections, electroporation, and surgery; ensure quality control and validation of models.
- Analytical Skills: Analyze and interpret genotyping data using various strategies to confirm model integrity and quality.
- Communication & Collaboration: Liaise with users, clients, and international partners (INFRAFRONTIER/EMMA), ensuring clear communication and excellent service delivery.
- Innovation & Research: Drive technological development by initiating new research projects aimed at developing innovative gene editing methods and new rodent or cell-based models.
Requirements
- A PhD or equivalent in molecular biology, genetics, cellular biology, medicine, or a related field, with experience in genome editing and transgenic technologies.
- A strong interest in learning and mastering new methods and techniques.
- Authorization to work with laboratory animals (rodents).
- Proven ability to lead and coordinate a team effectively.
- Proficiency in English (B2 or higher) and familiarity with office software and public databases.
- Experience with scientific publishing is an advantage.
We offer
- An engaging international environment within a leading scientific institution.
- Opportunities for professional growth, pursuing your own research, and participating in national and international collaborations.
- Data analysis and language courses.
- Participation in high-profile international conferences to showcase your research.
- Competitive salary and comprehensive benefits package (food allowance, kindergarten, sports/culture/pension contributions, and more).
- Flexible start date.
- Full-time position based in the CCP building on the BIOCEV campus in Vestec near Prague.
- Initially offered for 12 months with the possibility of extension based on performance.
How to apply
Applications consisting of covering letter and structured CV or questions related to the position should be sent to Mrs. Jana Šafránková (jana.safrankova@img.cas.cz).
We thank all applicants for their interest; however, only those selected for an interview will be contacted.
