Přednáška – Dr. Jens Volker
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Termín:
25. 6. 2013 | 15:00
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Místo:
IMG, posluchárna v přízemí
Jens is an expert on thermodynamics of DNA, especially of its unusual forms.
“Energy Landscapes of Stable and Metastable DNA States Implicated in Repeat DNA Expansion and Disease States” |
Dr. Jens Volker
Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey
Jens is an expert on thermodynamics of DNA, especially of its unusual forms.
References e.g.:
- Völker J, Gindikin V, Klump HH, Plum GE, Breslauer KJ:
Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: implications for DNA expansion associated with disease states. J. Am. Chem. Soc. (2012) 134: 6033-44. [doi]
- Völker J, Plum GE, Klump HH, Breslauer KJ:
Energy crosstalk between DNA lesions: implications for allosteric coupling of DNA repair and triplet repeat expansion pathways. J. Am. Chem. Soc. (2010) 132: 4095-7. [doi]
- Völker J, Klump HH, Breslauer KJ:
DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases. Proc. Natl. Acad. Sci. USA (2008) 105: 18326-30. [doi]
Host: Dr. Bohdan Schneider, Institute of Biotechnology AS CR