Laboratory of Leukocyte Signalling

Current Grants

Grant name Provider Duration Investigator Web
Mechanisms of the regulation of hematopoiesis and immune response by transmembrane adaptor protein WBP1L Czech Science Foundation 2021-2023 T. Brdička Go to website

Past Grants

Grant name Provider Duration Investigator Web
The effect of transmembrane domains of integral proteins on dynamic organisation of the plasma membrane of T lymphocytes Czech Science Foundation 2011-2014 T. Brdička Go to website
Function of Csk-anchoring proteins SCIMP and PSTPIP2 in leukocyte signaling and inflammation Czech Science Foundation 2012-2015 T. Brdička Go to website
Molecular mechanisms of signaling through leukocyte receptors their role in health and disease Czech Science Foundation 2012-2018 V. Hořejší, Pe. Dráber, D. Filipp Go to website
Phenotyping B- and T-cells in immunodeficiency Ministry of Health 2012-2015 T. Brdička Go to website
Organisation and function of CD4 co-receptor on the surface of T cells at nanoscale Czech Science Foundation 2015-2017 T. Brdička Go to website
Analysis of the role of transmembrane adaptor protein OPAL1 in the regulation of leukocyte receptor signaling with focus on chemokine receptor CXCR4 Czech Science Foundation 2016-2018 T. Brdička Go to website
Molecular mechanisms of the regulation of inflammatory responses by adaptor protein PSTPIP2 Czech Science Foundation 2017-2019 T. Brdička Go to website
Biochemical studies of membrane rafts and immunoreceptors based on cell membranedisintegrating copolymers Czech Science Foundation 2019-2021 V. Hořejší Go to website
The role of interactions of adaptor protein PSTPIP2 in the development of autoinflammatory disease Czech Science Foundation 2019-2021 T. Brdička Go to website
Topological regulation of CD4 and CD8 in T cells Czech Science Foundation 2019-2021 T. Brdička Go to website